Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001225Signal peptide, CUB domain, EGF-like 2. (991 aa)    
Predicted Functional Partners:
ENSACIP00000027464
APAF1 interacting protein.
    
  0.779
ENSACIP00000008092
Translocase of outer mitochondrial membrane 20.
    
 0.753
ENSACIP00000028410
ARID domain-containing protein.
    
 0.753
ENSACIP00000003652
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.689
ENSACIP00000023427
Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.
    
 0.689
ENSACIP00000023444
Sonic hedgehog signaling molecule a.
    
 0.689
ENOPH1
Enolase-phosphatase E1; Bifunctional enzyme that catalyzes the enolization of 2,3- diketo-5-methylthiopentyl-1-phosphate (DK-MTP-1-P) into the intermediate 2-hydroxy-3-keto-5-methylthiopentenyl-1-phosphate (HK- MTPenyl-1-P), which is then dephosphorylated to form the acireductone 1,2-dihydroxy-3-keto-5-methylthiopentene (DHK-MTPene).
     
  0.685
ENSACIP00000020191
Uncharacterized protein.
     
  0.685
ENSACIP00000005105
Iroquois homeobox 3a.
    
 
 0.673
ENSACIP00000027092
Usher syndrome 1C.
    
 
 0.672
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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