Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001308AT rich interactive domain 3C (BRIGHT-like). (602 aa)    
Predicted Functional Partners:
ENSACIP00000027770
POU domain protein.
    
 
 0.768
ENSACIP00000016790
Sap30-like.
    
 0.637
ENSACIP00000016361
Actin-like 6A; Belongs to the actin family.
    
 
 0.623
ENSACIP00000015006
Ig-like domain-containing protein.
      
 0.608
ENSACIP00000020373
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
  0.605
ENSACIP00000002362
WD repeat domain 73.
    
 0.598
ENSACIP00000020299
Retinoblastoma binding protein 4.
    
 0.598
ENSACIP00000022550
Uncharacterized protein.
    
 0.598
ENSACIP00000023695
Retinoblastoma binding protein 4, like.
    
 0.598
ENSACIP00000005692
Mortality factor 4 like 1.
   
 0.596
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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