Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001369Elongin A. (590 aa)    
Predicted Functional Partners:
ENSACIP00000001060
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.973
ENSACIP00000008651
Elongin B.
   
 0.963
ENSACIP00000018354
Ubiquitin-like domain-containing protein.
   
 0.963
ENSACIP00000000975
LEO1 homolog, Paf1/RNA polymerase II complex component.
    
 0.962
ENSACIP00000000330
CTR9 homolog, Paf1/RNA polymerase II complex component.
    
 0.927
ENSACIP00000020650
DNA-directed RNA polymerase subunit; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
   
 0.898
POLR2B
DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.
    
 0.857
ENSACIP00000006290
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
    
 0.851
ENSACIP00000016115
WD repeat domain 61.
    
 0.844
CUL5
Cullin 5; Belongs to the cullin family.
    
 
 0.806
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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