Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000001370Thiamine pyrophosphokinase; Belongs to the thiamine pyrophosphokinase family. (328 aa)    
Predicted Functional Partners:
ENSACIP00000028114
Thiamine triphosphatase.
    
 0.950
ENSACIP00000022170
Adenylate kinase 5; Belongs to the adenylate kinase family.
     
 0.922
AK1
Adenylate kinase isoenzyme 1; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Also displays broad nucleoside diphosphate kinase activity. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.
     
 0.922
ENSACIP00000025658
Uncharacterized protein; Belongs to the adenylate kinase family.
     
 0.922
ENSACIP00000007887
Uncharacterized protein; Belongs to the adenylate kinase family.
     
 0.908
ENSACIP00000012391
Uncharacterized protein.
     
 0.878
ENSACIP00000015927
Uncharacterized protein.
     
 0.878
ENSACIP00000007617
LMWPc domain-containing protein.
    
  0.874
ENSACIP00000007668
Adenylate kinase 8; Belongs to the adenylate kinase family.
     
 0.872
ENSACIP00000015892
Adenylate kinase 4; Belongs to the adenylate kinase family.
     
 0.872
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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