Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001402Cyclic AMP-dependent transcription factor ATF-7; Plays important functions in early cell signaling. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AG][AG]-3'), a sequence present in many viral and cellular promoters. (475 aa)    
Predicted Functional Partners:
ENSACIP00000021168
Cyclic AMP-responsive element-binding protein 5; Binds to the cAMP response element and activates transcription.
    
  0.972
ENSACIP00000020437
CREB binding protein b.
   
 0.956
ENSACIP00000020520
CREB binding protein a.
   
 0.956
ENSACIP00000016064
JunE proto-oncogene, AP-1 transcription factor subunit.
   
 0.952
ENSACIP00000005536
Activating transcription factor 4a.
    
 0.931
ENSACIP00000010497
Activating transcription factor 4b.
    
 0.925
ENSACIP00000021550
Mitogen-activated protein kinase.
   
 0.918
ENSACIP00000007539
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.908
ENSACIP00000008799
Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.
    
 0.908
ENSACIP00000022036
Mitogen-activated protein kinase.
    
 0.908
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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