STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)    
Predicted Functional Partners:
ENSACIP00000006577
Uncharacterized protein.
    
 0.979
ENSACIP00000010685
Phosphoinositide-3-kinase, regulatory subunit 5.
   
 0.978
ENSACIP00000015432
Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).
    
 0.978
ENSACIP00000019273
Phosphoinositide-3-kinase, regulatory subunit 1 (alpha).
    
 0.978
ENSACIP00000026363
Phosphoinositide-3-kinase, regulatory subunit 2 (beta).
    
 0.978
ENSACIP00000013559
Uncharacterized protein.
    
 0.972
ENSACIP00000025102
Uncharacterized protein.
    
 0.972
MRAS
Muscle RAS oncogene homolog.
   
 0.969
ENSACIP00000019186
Serine/threonine-protein kinase TOR; Belongs to the PI3/PI4-kinase family.
    
 0.959
ENSACIP00000008614
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.
   
0.951
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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