STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001425Carboxypeptidase B2 (plasma). (440 aa)    
Predicted Functional Partners:
C8A
Complement C8 alpha chain.
   
  
 0.758
ENSACIP00000012091
Coagulation factor VII.
  
 
 0.733
ENSACIP00000007256
Angiotensinogen; Belongs to the serpin family.
   
 
  0.637
ENSACIP00000012117
Coagulation factor VIIi.
  
 
 0.620
ENSACIP00000012222
Coagulation factor X.
  
 
 0.620
ENSACIP00000012312
Coagulation factor X.
  
 
 0.620
ENSACIP00000012341
Coagulation factor X; Belongs to the peptidase S1 family.
  
 
 0.620
ENSACIP00000006197
Uncharacterized protein.
  
 
 0.589
ENSACIP00000024238
Serpin peptidase inhibitor, clade D (heparin cofactor), member 1; Belongs to the serpin family.
   
 
 0.562
ENSACIP00000002522
Plasminogen; Plasmin dissolves the fibrin of blood clots and acts as a proteolytic factor in a variety of other processes including embryonic development, tissue remodeling, tumor invasion, and inflammation. In ovulation, weakens the walls of the Graafian follicle. It activates the urokinase-type plasminogen activator, collagenases and several complement zymogens, such as C1 and C5. Cleavage of fibronectin and laminin leads to cell detachment and apoptosis. Also cleaves fibrin, thrombospondin and von Willebrand factor. Its role in tissue remodeling and tumor invasion may be modulated b [...]
  
 
 0.556
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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