Nodes:
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
IWS1Interacts with SUPT6H, CTD assembly factor 1. (616 aa)    
Predicted Functional Partners:
ENSACIP00000006290
Transcription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family.
   
 0.999
ENSACIP00000000975
LEO1 homolog, Paf1/RNA polymerase II complex component.
   
 0.985
ENSACIP00000008327
FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...]
   
 0.982
ENSACIP00000000330
CTR9 homolog, Paf1/RNA polymerase II complex component.
   
 0.978
ENSACIP00000012372
SPT16 homolog, facilitates chromatin remodeling subunit.
   
 0.976
ENSACIP00000015644
Polymerase (RNA) II (DNA directed) polypeptide C.
    
 0.974
ENSACIP00000027506
Transcription elongation factor SPT5.
   
 0.974
ENSACIP00000015663
SPT4 homolog, DSIF elongation factor subunit.
    
 0.972
ENSACIP00000019275
Uncharacterized protein.
   
 
 0.968
ENSACIP00000007983
RNA polymerase II subunit A C-terminal domain phosphatase; This promotes the activity of RNA polymerase II.
   
 
 0.964
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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