Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000001483Suppressor of cytokine signaling 3. (228 aa)    
Predicted Functional Partners:
ENSACIP00000016014
Leptin receptor.
    
 0.976
ENSACIP00000022238
Suppressor of cytokine signaling 1a.
   
 
0.966
ENSACIP00000001060
Elongin C paralog a; Belongs to the SKP1 family.
    
 0.965
ENSACIP00000012506
Suppressor of cytokine signaling 2.
    
0.952
ENSACIP00000008845
Suppressor of cytokine signaling 9.
     
 0.949
ENSACIP00000013991
Uncharacterized protein.
   
 0.942
ENSACIP00000019454
Suppressor of cytokine signaling 1b.
     
 
0.934
CUL5
Cullin 5; Belongs to the cullin family.
    
 0.932
ENSACIP00000022008
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.932
ENSACIP00000027848
Suppressor of cytokine signaling 4.
     
0.932
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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