Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ARL3ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (160 aa)    
Predicted Functional Partners:
ENSACIP00000007167
Protein XRP2; Acts as a GTPase-activating protein (GAP) for tubulin in concert with tubulin-specific chaperone C, but does not enhance tubulin heterodimerization.
    
 0.973
ENSACIP00000025261
Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta; Promotes the release of prenylated target proteins from cellular membranes. Modulates the activity of prenylated or palmitoylated Ras family members by regulating their subcellular location. Required for normal ciliary targeting of farnesylated target proteins, such as INPP5E. Modulates the subcellular location of target proteins by acting as a GTP specific dissociation inhibitor (GDI). Increases the affinity of ARL3 for GTP by several orders of magnitude. Stabilizes ARL3-GTP by decreasing the nucleotide [...]
   
 0.971
ENSACIP00000023128
GMP_PDE_delta domain-containing protein.
    
 0.940
UNC119
Unc-119 lipid binding chaperone.
    
 0.940
ENSACIP00000012862
Cilia and flagella associated protein 36.
   
 
 0.929
ENSACIP00000012220
Tubulin folding cofactor C.
    
 0.910
ENSACIP00000002806
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2.
    
 0.897
ENSACIP00000018816
Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1.
    
 0.897
ENSACIP00000006671
ADP-ribosylation factor-like 2 binding protein.
    
 
 0.875
ENSACIP00000023751
Nephronophthisis 3.
   
 0.817
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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