Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001658Methyltransferase-like protein; Belongs to the methyltransferase superfamily. METL family. (394 aa)    
Predicted Functional Partners:
ENSACIP00000015436
Thyroid hormone receptor interactor 12.
    
   0.875
ENSACIP00000006958
Seryl-tRNA synthetase.
    
 
 0.710
EEF1AKMT2
EEF1A lysine methyltransferase 2; Protein-lysine methyltransferase that selectively catalyzes the trimethylation of EEF1A at 'Lys-318'; Belongs to the class I-like SAM-binding methyltransferase superfamily. EFM4 family.
   
  
 0.659
ENSACIP00000015707
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.643
ENSACIP00000023977
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 
 0.643
ENSACIP00000005215
Methyltransferase like 25.
      
 0.642
ENSACIP00000031686
Pseudouridylate synthase 3.
   
  
 0.609
ENSACIP00000002120
Methyltransferase like 5.
   
  
 0.603
ENSACIP00000002656
Seryl-tRNA synthetase 2, mitochondrial.
    
 
 0.597
ENSACIP00000021545
tRNA methyltransferase 10A.
   
  
 0.594
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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