Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
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Co-occurrence
Co-expression
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[Homology]
Score
ENSACIP00000001709SMG5 nonsense mediated mRNA decay factor. (1029 aa)    
Predicted Functional Partners:
ENSACIP00000019495
SMG7 nonsense mediated mRNA decay factor.
   
0.998
ENSACIP00000016724
SMG6 nonsense mediated mRNA decay factor.
   
0.997
ENSACIP00000017438
UPF3B regulator of nonsense mediated mRNA decay.
   
 0.993
UPF1
UPF1 RNA helicase and ATPase.
   
 0.990
ENSACIP00000025783
Uncharacterized protein.
   
 0.990
ENSACIP00000026483
UPF3A regulator of nonsense mediated mRNA decay.
   
 0.984
ENSACIP00000031575
SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family.
    
 0.971
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
   
 0.968
ENSACIP00000022588
Telomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
   
 0.965
ENSACIP00000011818
SMG9 nonsense mediated mRNA decay factor.
   
 
 0.960
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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