Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000001797Uncharacterized protein. (274 aa)    
Predicted Functional Partners:
ENSACIP00000004406
Laccase (multicopper oxidoreductase) domain containing 1.
   
  
 0.621
ENSACIP00000000838
Coiled-coil domain containing 137.
      
 0.617
ENSACIP00000023257
Solute carrier family 7 member 14b.
      
 0.592
ENSACIP00000000408
Receptor-interacting serine-threonine kinase 2.
      
 0.589
ENSACIP00000008387
Guanine nucleotide binding protein (G protein), alpha 15 (Gq class), tandem duplicate 4.
      
 0.453
ISYNA1
Inositol-3-phosphate synthase 1.
      
 0.451
ENSACIP00000007770
Solute carrier family 7 member 14a.
      
 0.439
ENSACIP00000028424
SPRY domain containing 7b.
      
 0.435
ENSACIP00000021053
Si:dkey-72l14.4.
    
   0.421
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
      
 0.414
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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