Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000001805TBC1 domain family, member 23. (663 aa)    
Predicted Functional Partners:
OSGEP
Probable tRNA N6-adenosine threonylcarbamoyltransferase; Component of the EKC/KEOPS complex that is required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. The complex is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37. OSGEP likely plays a direct catalytic role in this reaction, but requires other protein(s) of the complex to fulfill this activity.
    
   0.973
ENSACIP00000028285
Glutaredoxin 3.
    
   0.973
ENSACIP00000014924
Family with sequence similarity 91 member A1.
   
 
 0.969
ENSACIP00000015265
Apoptosis inhibitor 5.
   
   0.933
ENSACIP00000010124
Zgc:153240.
      
 0.848
ENSACIP00000002118
TBC1 domain family, member 5.
   
  
 0.651
ENSACIP00000026525
Cell division cycle 16 homolog (S. cerevisiae).
      
 0.640
ENSACIP00000007958
Adaptor related protein complex 1 associated regulatory protein.
      
 0.639
ENSACIP00000028424
SPRY domain containing 7b.
      
 0.637
ENSACIP00000010771
Synergin, gamma.
      
 0.635
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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