STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001807GA binding protein transcription factor subunit beta 2a. (435 aa)    
Predicted Functional Partners:
ENSACIP00000029532
GA binding protein transcription factor subunit alpha.
    
 0.986
ENSACIP00000014941
Caspase 2, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.
    
  0.861
ENSACIP00000020735
DNA-directed RNA polymerase; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the phage and mitochondrial RNA polymerase family.
    
 0.707
ENSACIP00000010178
Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes.
    
  0.692
ENSACIP00000028551
Tumor protein p73; Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.
    
  0.692
ENSACIP00000006222
Cathepsin Bb; Belongs to the peptidase C1 family.
   
   0.686
ENSACIP00000010750
Cathepsin Ba; Belongs to the peptidase C1 family.
   
   0.686
ENSACIP00000011851
Tpd52 like 2b.
    
  0.685
ENSACIP00000030409
Ribosomal protein S3; Belongs to the universal ribosomal protein uS3 family.
    
 0.673
ENSACIP00000014612
Tpd52 like 2a.
    
  0.664
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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