Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001876Si:ch211-253p14.2. (425 aa)    
Predicted Functional Partners:
ENSACIP00000006062
CULLIN_2 domain-containing protein; Belongs to the cullin family.
    
 0.772
CUL3
Cullin 3; Belongs to the cullin family.
    
 0.772
ENSACIP00000008151
COMM domain containing 5.
  
  
  0.661
ENSACIP00000012470
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.633
ENSACIP00000022055
COMM domain containing 9.
     
  0.582
ENSACIP00000008910
COMM domain containing 8.
     
  0.564
ENSACIP00000011622
COMM domain containing 7.
     
  0.564
ENSACIP00000027143
COMM domain containing 6.
     
  0.564
ENSACIP00000009273
Coiled-coil domain containing 22.
     
  0.543
ENSACIP00000004396
Uncharacterized protein.
      
 0.535
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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