Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000001909Rhomboid domain containing 2. (335 aa)    
Predicted Functional Partners:
ENSACIP00000019939
MICOS complex subunit MIC13; Component of the MICOS complex, a large protein complex of the mitochondrial inner membrane that plays crucial roles in the maintenance of crista junctions, inner membrane architecture, and formation of contact sites to the outer membrane.
    
 
 0.739
ENSACIP00000015359
Dolichol phosphate-mannose biosynthesis regulatory protein; Regulatory subunit of the dolichol-phosphate mannose (DPM) synthase complex; essential for the ER localization. Belongs to the DPM2 family.
     
  0.712
ENSACIP00000023660
Phosphatidylinositol glycan anchor biosynthesis, class Q.
     
  0.712
ENSACIP00000002294
Phosphatidylinositol glycan anchor biosynthesis, class H.
     
  0.708
ENSACIP00000014169
Phosphatidylinositol glycan anchor biosynthesis, class L.
     
  0.705
ENSACIP00000023376
Phosphatidylinositol N-acetylglucosaminyltransferase subunit P; Part of the complex catalyzing the transfer of N- acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol, the first step of GPI biosynthesis.
     
  0.698
ENSACIP00000025700
CDP-diacylglycerol--inositol 3-phosphatidyltransferase.
   
 
  0.680
ENSACIP00000015024
BRO1 domain and CAAX motif containing.
      
 0.654
ENSACIP00000003132
Uncharacterized protein.
      
 0.638
ENSACIP00000013958
Rhomboid domain containing 3.
      
 0.638
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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