Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000001983Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (255 aa)    
Predicted Functional Partners:
ENSACIP00000030923
Fibroblast growth factor receptor.
    
 0.979
ENSACIP00000006012
Fibroblast growth factor receptor 2.
    
 0.976
FGFR1
Fibroblast growth factor receptor.
    
 0.975
ENSACIP00000003046
Fibroblast growth factor receptor.
    
 0.970
ENSACIP00000010676
Uncharacterized protein.
    
 0.955
ENSACIP00000010712
Uncharacterized protein.
    
 0.955
ENSACIP00000010767
Fibroblast growth factor receptor.
    
 0.955
ENSACIP00000025824
Fibroblast growth factor; Belongs to the heparin-binding growth factors family.
   
 
 0.949
ENSACIP00000004492
Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands.
    
 0.940
ENSACIP00000001698
KIT proto-oncogene, receptor tyrosine kinase b; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
    
 0.923
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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