Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000001984TNFR-Cys domain-containing protein. (248 aa)    
Predicted Functional Partners:
ENSACIP00000025236
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.916
ENSACIP00000013761
TNF receptor-associated factor.
    
 0.891
ENSACIP00000020936
TNF receptor-associated factor.
    
 0.891
ENSACIP00000019196
TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family.
    
 0.886
ENSACIP00000022616
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.885
ENSACIP00000029422
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.885
ENSACIP00000028315
Tumor necrosis factor b (TNF superfamily, member 2).
   
 0.877
ENSACIP00000015060
CD40 ligand; Belongs to the tumor necrosis factor family.
    
 0.822
ENSACIP00000022320
TNF superfamily member 14; Belongs to the tumor necrosis factor family.
     
  0.819
ENSACIP00000007924
Uncharacterized protein.
   
 
  0.803
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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