Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (197 aa)    
Predicted Functional Partners:
ENSACIP00000006012
Fibroblast growth factor receptor 2.
    
 0.949
FGFR1
Fibroblast growth factor receptor.
    
 0.949
ENSACIP00000030923
Fibroblast growth factor receptor.
    
 0.949
ENSACIP00000010676
Uncharacterized protein.
    
 0.924
ENSACIP00000010712
Uncharacterized protein.
    
 0.924
ENSACIP00000010767
Fibroblast growth factor receptor.
    
 0.924
ENSACIP00000020852
Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily.
   
 0.922
ENSACIP00000003046
Fibroblast growth factor receptor.
    
 0.918
ENSACIP00000028372
Protein kinase domain-containing protein.
   
 0.916
ENSACIP00000030288
Platelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development.
   
 0.916
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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