Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000002114DDE Tnp4 domain-containing protein. (365 aa)    
Predicted Functional Partners:
ENSACIP00000007756
Sortilin-related receptor, L(DLR class) A repeats containing.
    
 0.741
ENSACIP00000010143
Glyoxalase domain containing 4.
    
  0.686
ENSACIP00000016909
Uncharacterized protein.
   
 0.671
ENSACIP00000027073
Uncharacterized protein.
   
 0.671
ENSACIP00000009836
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
  0.565
ENSACIP00000006811
Methylmalonyl CoA epimerase.
    
  0.532
GLO1
Glyoxalase I.
    
  0.532
ENSACIP00000012230
Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family.
     
 0.527
ENSACIP00000006894
Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family.
     
 0.513
ENSACIP00000000485
Zinc finger protein.
     
  0.510
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
Server load: low (16%) [HD]