Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000002118TBC1 domain family, member 5. (768 aa)    
Predicted Functional Partners:
ENSACIP00000030841
Vacuolar protein sorting-associated protein 29; Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway.
    
 
 0.991
ENSACIP00000030872
Vacuolar protein sorting-associated protein 35; Plays a role in vesicular protein sorting.
   
 
 0.991
ENSACIP00000008689
VPS26, retromer complex component A.
   
 
 0.990
SNX27
Sorting nexin 27.
    
 
 0.961
ENSACIP00000009193
VPS26, retromer complex component B.
   
 
 0.950
ENSACIP00000022805
Uncharacterized protein.
   
 
 0.950
ENSACIP00000004863
Leucine rich repeat containing 73.
    
   0.893
ENSACIP00000021065
Autophagy-related protein 9; Involved in autophagy and cytoplasm to vacuole transport (Cvt) vesicle formation. Plays a key role in the organization of the preautophagosomal structure/phagophore assembly site (PAS), the nucleating site for formation of the sequestering vesicle. Belongs to the ATG9 family.
    
 
 0.879
ENSACIP00000024377
Uncharacterized protein.
    
 
 0.879
ENSACIP00000017858
RAB7a, member RAS oncogene family.
    
 
 0.851
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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