Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000002156Uncharacterized protein. (678 aa)    
Predicted Functional Partners:
MPP5
Membrane palmitoylated protein 5; Belongs to the MAGUK family.
    
 0.869
ENSACIP00000018280
Membrane protein, palmitoylated 5b (MAGUK p55 subfamily member 5); Belongs to the MAGUK family.
    
 0.869
NCSTN
Nicastrin.
    
 0.659
ENSACIP00000028175
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.650
ENSACIP00000015707
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.622
ENSACIP00000023977
Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.
    
 0.622
ENSACIP00000002357
NUMB like endocytic adaptor protein.
    
 0.605
ENSACIP00000015472
NUMB endocytic adaptor protein.
    
 0.605
ENSACIP00000025422
Mastermind-like transcriptional coactivator 1.
    
 0.603
ENSACIP00000018528
Recombination signal binding protein for immunoglobulin kappa J region a.
    
 0.601
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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