Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
MARCHF6Membrane associated ring-CH-type finger 6. (918 aa)    
Predicted Functional Partners:
ENSACIP00000004221
Squalene epoxidase a.
    
 
 0.942
ENSACIP00000024551
Ubiquitin-conjugating enzyme E2G 2 (UBC7 homolog, yeast); Belongs to the ubiquitin-conjugating enzyme family.
    
 
 0.942
ENSACIP00000019711
Ubiquitin-conjugating enzyme E2, J2 (UBC6 homolog, yeast).
    
 
 0.906
ENSACIP00000008011
Synovial apoptosis inhibitor 1, synoviolin.
    
 
 0.868
ENSACIP00000028139
Autocrine motility factor receptor b.
    
 
 0.868
ENSACIP00000003610
RING-CH-type domain-containing protein.
     
  0.865
ENSACIP00000003640
Ankyrin repeat domain 33Bb.
     
  0.861
ENSACIP00000021778
C1q and TNF related 12.
    
 
 0.854
ENSACIP00000025994
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
    
 0.780
CNOT2
CCR4-NOT transcription complex subunit 2.
    
 
 0.775
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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