Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
ENSACIP0000000222910-formyltetrahydrofolate dehydrogenase; In the C-terminal section; belongs to the aldehyde dehydrogenase family. ALDH1L subfamily. (894 aa)    
Predicted Functional Partners:
ENSACIP00000021944
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
  
 
 0.953
ENSACIP00000024840
MGS domain-containing protein.
  
 
 0.938
ENSACIP00000003211
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
 0.932
ENSACIP00000008686
Dihydrofolate reductase.
    
 0.927
ENSACIP00000009872
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1 like.
  
 
 0.918
ENSACIP00000019453
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1b.
  
 
 0.918
ENSACIP00000022323
Aminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family.
  
 
 0.904
ENSACIP00000011029
Zgc:153031.
    
 0.903
ENSACIP00000001829
THF_DHG_CYH domain-containing protein.
  
 
 0.902
ENSACIP00000026826
Methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like.
  
 
 0.902
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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