Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000002267Ankyrin repeat and kinase domain containing 1. (744 aa)    
Predicted Functional Partners:
ENSACIP00000002177
Uncharacterized protein.
   
 
 0.891
ENSACIP00000005765
TGF-beta activated kinase 1/MAP3K7 binding protein 1.
   
 0.788
ENSACIP00000017342
NBR1 autophagy cargo receptor a.
    
 0.777
ENSACIP00000024243
NBR1 autophagy cargo receptor b.
    
 0.777
ENSACIP00000027317
TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.
    
 0.761
ENSACIP00000018368
Mindbomb E3 ubiquitin protein ligase 2.
   
 0.750
ENSACIP00000009916
Mitogen-activated protein kinase kinase 7.
   
 0.749
ENSACIP00000013246
Catechol-O-methyltransferase b.
      
 0.716
ENSACIP00000026146
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
 0.713
ENSACIP00000022758
Immunoglobulin superfamily, member 3.
    
 0.705
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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