Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
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[Homology]
Score
ENSACIP00000002269Kelch-like family member 23. (562 aa)    
Predicted Functional Partners:
ENSACIP00000020155
SET domain containing 4.
      
 0.741
ENSACIP00000003162
Inhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family.
      
 0.610
ENSACIP00000018421
UBX domain-containing protein 7.
    
  0.610
ENSACIP00000007832
Bardet-Biedl syndrome 9.
    
 0.581
ENSACIP00000009943
Tetratricopeptide repeat domain 8.
    
 0.561
ENSACIP00000024327
Bardet-Biedl syndrome 7.
    
 0.537
ENSACIP00000021174
BBSome interacting protein 1.
    
  0.495
ENSACIP00000002504
Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
    
 0.471
ENSACIP00000026537
SLIT-ROBO Rho GTPase activating protein 3.
      
 0.466
ENSACIP00000018368
Mindbomb E3 ubiquitin protein ligase 2.
    
 0.461
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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