Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
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[Homology]
Score
ENSACIP00000002302Serine hydrolase like. (289 aa)    
Predicted Functional Partners:
ENSACIP00000019833
Malate synthase-like.
  
 
 0.818
ENSACIP00000022079
Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.
   
 0.718
ENSACIP00000015554
Isochorismatase domain containing 2.
  
 0.649
ENSACIP00000021684
Hydroxysteroid dehydrogenase like 2.
  
 0.619
ENSACIP00000004509
Succinyl-CoA:3-ketoacid-coenzyme A transferase; Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.
  
 
 0.613
ENSACIP00000029937
Aminoadipate-semialdehyde dehydrogenase.
    
 0.610
IYD
Iodotyrosine deiodinase.
  
 
 0.591
ENSACIP00000009407
Nudix (nucleoside diphosphate linked moiety X)-type motif 12.
   
  0.584
ENSACIP00000025650
Leucine-rich repeats and guanylate kinase domain containing.
   
 0.580
ENSACIP00000031136
2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3).
    
 0.578
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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