Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000002541Uncharacterized protein. (727 aa)    
Predicted Functional Partners:
ENSACIP00000002494
DNA polymerase.
     
 0.743
ENSACIP00000021372
Dynactin 2 (p50).
    
 
 0.709
PLCB4
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
      
 0.691
ENSACIP00000021944
Trifunctional purine biosynthetic protein adenosine-3; In the C-terminal section; belongs to the GART family. In the central section; belongs to the AIR synthase family.
     
  0.657
ENSACIP00000001574
Uncharacterized protein.
    
  0.652
ENSACIP00000024340
Uncharacterized protein.
    
  0.652
ENSACIP00000016064
JunE proto-oncogene, AP-1 transcription factor subunit.
    
 0.613
ENSACIP00000017661
Myb-like, SWIRM and MPN domains 1.
   
  0.613
ENSACIP00000018817
SH3 domain-containing protein.
  
   
 0.604
ENSACIP00000016380
40S ribosomal protein S4; Belongs to the eukaryotic ribosomal protein eS4 family.
   
 
 0.603
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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