Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000002579Protein kinase domain-containing protein. (73 aa)    
Predicted Functional Partners:
ENSACIP00000007861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.983
ENSACIP00000026160
Cyclin B1; Belongs to the cyclin family.
   
 0.977
ENSACIP00000003087
Cyclin D1; Belongs to the cyclin family.
   
 0.974
ENSACIP00000022249
Cyclin N-terminal domain-containing protein; Belongs to the cyclin family.
   
 0.974
ENSACIP00000030445
Cyclin A1; Belongs to the cyclin family.
   
 0.972
CDKN2B
Cyclin dependent kinase inhibitor 2B.
    
 0.968
ENSACIP00000004062
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.966
ENSACIP00000006083
Cyclin B3; Belongs to the cyclin family.
   
 0.966
ENSACIP00000020012
Retinoblastoma 1.
   
 0.966
ENSACIP00000003458
Cyclin B2; Belongs to the cyclin family.
   
 0.964
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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