Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000003033TBC1 domain family, member 2B. (882 aa)    
Predicted Functional Partners:
ENSACIP00000019042
NRDE-2, necessary for RNA interference, domain containing.
    
 0.872
ENSACIP00000029324
Uncharacterized protein.
    
   0.749
ENSACIP00000029330
WD_REPEATS_REGION domain-containing protein.
    
   0.749
FAM124A
Family with sequence similarity 124 member A.
      
 0.742
ENSACIP00000017858
RAB7a, member RAS oncogene family.
    
 0.737
ENSACIP00000028882
Uncharacterized protein.
    
 0.737
ENSACIP00000028893
RAB7A, member RAS oncogene family.
    
 0.737
ENSACIP00000001813
NDK domain-containing protein.
    
 
 0.699
ENSACIP00000003254
Serine/threonine-protein kinase PLK.
    
 0.694
ENSACIP00000006663
Protein kinase domain-containing protein.
    
 0.694
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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