Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP000000030443-hydroxyisobutyrate dehydrogenase; Belongs to the HIBADH-related family. (314 aa)    
Predicted Functional Partners:
ENSACIP00000006460
3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family.
 
 0.989
ENSACIP00000005183
Aldedh domain-containing protein.
   
 0.974
ALDH6A1
Aldehyde dehydrogenase 6 family member A1.
   
 0.974
ENSACIP00000000840
Acyl-CoA dehydrogenase short/branched chain.
  
 0.935
ENSACIP00000011184
Acyl-CoA dehydrogenase short chain.
  
 0.935
ENSACIP00000007376
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.
    
 0.924
ENSACIP00000006681
Integrator complex subunit 1.
   
 0.914
ENSACIP00000007425
Aldehyde dehydrogenase 2 family member, tandem duplicate 2; Belongs to the aldehyde dehydrogenase family.
   
 0.911
ENSACIP00000010857
Aldehyde dehydrogenase 16 family, member A1.
   
 0.911
ENSACIP00000019925
Aldehyde dehydrogenase 9 family, member A1a, tandem duplicate 1; Belongs to the aldehyde dehydrogenase family.
   
 0.911
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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