KMT2A protein (Amphilophus citrinellus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Knowledge-based Evidence

from curated databases

textmining

Assay-based Predictions

experimentally determined

co-expression

Genomic Predictions

gene neighborhood

gene co-occurrence

gene fusions

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

KMT2A

Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4225 aa)

Predicted Functional Partners:

ENSACIP00000013550

0.987

ENSACIP00000017789

0.982

ENSACIP00000001761

0.980

ENSACIP00000021054

0.980

ENSACIP00000014300

0.964

ENSACIP00000018347

0.942

ENSACIP00000024301

0.938

ENSACIP00000019275

0.913

ENSACIP00000010818

0.902

ENSACIP00000020437

0.900

Your Current Organism:

Amphilophus citrinellus

NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSACIP00000001761	ENSACIP00000013550	ENSACIP00000001761	ENSACIP00000013550	WD repeat domain 5.	Retinoblastoma binding protein 5.	0.999
ENSACIP00000001761	ENSACIP00000017789	ENSACIP00000001761	ENSACIP00000017789	WD repeat domain 5.	Ash2 like, histone lysine methyltransferase complex subunit.	0.999
ENSACIP00000001761	ENSACIP00000019275	ENSACIP00000001761	ENSACIP00000019275	WD repeat domain 5.	Uncharacterized protein.	0.571
ENSACIP00000001761	ENSACIP00000020437	ENSACIP00000001761	ENSACIP00000020437	WD repeat domain 5.	CREB binding protein b.	0.600
ENSACIP00000001761	ENSACIP00000021054	ENSACIP00000001761	ENSACIP00000021054	WD repeat domain 5.	Multiple endocrine neoplasia I.	0.994
ENSACIP00000001761	ENSACIP00000024301	ENSACIP00000001761	ENSACIP00000024301	WD repeat domain 5.	PWWP domain-containing protein.	0.703
ENSACIP00000001761	KMT2A	ENSACIP00000001761	ENSACIP00000003045	WD repeat domain 5.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.980
ENSACIP00000010818	ENSACIP00000013550	ENSACIP00000010818	ENSACIP00000013550	Uncharacterized protein.	Retinoblastoma binding protein 5.	0.570
ENSACIP00000010818	ENSACIP00000017789	ENSACIP00000010818	ENSACIP00000017789	Uncharacterized protein.	Ash2 like, histone lysine methyltransferase complex subunit.	0.644
ENSACIP00000010818	ENSACIP00000018347	ENSACIP00000010818	ENSACIP00000018347	Uncharacterized protein.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.908
ENSACIP00000010818	ENSACIP00000019275	ENSACIP00000010818	ENSACIP00000019275	Uncharacterized protein.	Uncharacterized protein.	0.965
ENSACIP00000010818	ENSACIP00000020437	ENSACIP00000010818	ENSACIP00000020437	Uncharacterized protein.	CREB binding protein b.	0.562
ENSACIP00000010818	KMT2A	ENSACIP00000010818	ENSACIP00000003045	Uncharacterized protein.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.902
ENSACIP00000013550	ENSACIP00000001761	ENSACIP00000013550	ENSACIP00000001761	Retinoblastoma binding protein 5.	WD repeat domain 5.	0.999
ENSACIP00000013550	ENSACIP00000010818	ENSACIP00000013550	ENSACIP00000010818	Retinoblastoma binding protein 5.	Uncharacterized protein.	0.570
ENSACIP00000013550	ENSACIP00000014300	ENSACIP00000013550	ENSACIP00000014300	Retinoblastoma binding protein 5.	Ash1 (absent, small, or homeotic)-like (Drosophila).	0.610
ENSACIP00000013550	ENSACIP00000017789	ENSACIP00000013550	ENSACIP00000017789	Retinoblastoma binding protein 5.	Ash2 like, histone lysine methyltransferase complex subunit.	0.999
ENSACIP00000013550	ENSACIP00000018347	ENSACIP00000013550	ENSACIP00000018347	Retinoblastoma binding protein 5.	Histone-lysine N-methyltransferase, H3 lysine-79 specific.	0.419
ENSACIP00000013550	ENSACIP00000019275	ENSACIP00000013550	ENSACIP00000019275	Retinoblastoma binding protein 5.	Uncharacterized protein.	0.817
ENSACIP00000013550	ENSACIP00000020437	ENSACIP00000013550	ENSACIP00000020437	Retinoblastoma binding protein 5.	CREB binding protein b.	0.864

page 1 of 5

Server load: low (18%) [HD]

Permalink

Network

Cooccurrence

Experiments

Coexpression

Databases

Neighborhood

Textmining

Fusion

© STRING Consortium 2026

Credits

Access

Info

About