Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000003052Zgc:158803. (418 aa)    
Predicted Functional Partners:
SNRPC
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]
    
 0.940
ENSACIP00000018202
RNA binding motif protein 25b.
   
 0.935
ENSACIP00000025181
RNA binding motif protein 25a.
   
 0.935
ENSACIP00000000604
LUC7-like 3 pre-mRNA splicing factor.
   
0.921
ENSACIP00000023047
Small nuclear ribonucleoprotein 70 (U1).
   
 0.918
ENSACIP00000025263
Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.
   
 0.900
ENSACIP00000008343
Small nuclear ribonucleoprotein G.
   
 0.899
NCBP1
Nuclear cap binding protein subunit 1.
    
 
 0.896
ENSACIP00000027512
Small nuclear ribonucleoprotein polypeptide A.
   
 0.896
ENSACIP00000017055
Small nuclear ribonucleoprotein polypeptide F.
   
 0.893
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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