Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000003087Cyclin D1; Belongs to the cyclin family. (292 aa)    
Predicted Functional Partners:
ENSACIP00000007861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
    
 0.985
ENSACIP00000026696
Cyclin-dependent kinase 6; Belongs to the protein kinase superfamily.
   
 0.978
ENSACIP00000020012
Retinoblastoma 1.
    
 0.976
ENSACIP00000002568
Cyclin-dependent kinase 4.
   
 0.974
ENSACIP00000002579
Protein kinase domain-containing protein.
   
 0.974
ENSACIP00000013724
Retinoblastoma-like 1 (p107).
    
 0.970
ENSACIP00000023919
Retinoblastoma-like 2 (p130).
    
 0.970
ENSACIP00000025350
Cyclin-dependent kinase inhibitor 1A.
   
 0.969
ENSACIP00000011129
ANK_REP_REGION domain-containing protein.
    
 0.968
ENSACIP00000023306
Uncharacterized protein.
   
 0.960
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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