Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
PRICKLE1Prickle homolog 1a. (821 aa)    
Predicted Functional Partners:
VANGL1
Vang-like protein.
    
 0.986
ENSACIP00000009541
Vang-like protein.
    
 0.980
VANGL2
Vang-like protein.
    
 0.980
ENSACIP00000021823
Dishevelled segment polarity protein 2.
    
 0.977
ENSACIP00000012587
Dishevelled segment polarity protein 1a.
    
 0.964
ENSACIP00000024981
Dishevelled segment polarity protein 3a.
    
 0.955
ENSACIP00000022692
Vang-like protein.
    
 0.921
ENSACIP00000004678
Ankyrin repeat domain 6b.
    
 0.871
ENSACIP00000012484
T-box transcription factor 1.
      
 0.868
ENSACIP00000011493
Prickle homolog 2b.
     
  0.865
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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