Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000003261Epidermal growth factor. (948 aa)    
Predicted Functional Partners:
ENSACIP00000018242
Receptor protein-tyrosine kinase.
   
 0.983
ENSACIP00000020589
Receptor protein-tyrosine kinase.
   
 0.982
ENSACIP00000025809
Protein kinase domain-containing protein.
   
 0.982
ENSACIP00000021504
Erb-b2 receptor tyrosine kinase 3b.
   
 0.969
ENSACIP00000031132
Receptor protein-tyrosine kinase.
   
 0.969
ENSACIP00000017020
Receptor protein-tyrosine kinase.
   
 0.968
ENSACIP00000029515
Protein kinase domain-containing protein.
   
 0.968
ENSACIP00000029571
Uncharacterized protein.
   
 0.968
ENSACIP00000021506
Transforming growth factor, alpha.
     
 0.950
ENSACIP00000022828
Vascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family.
     
 0.948
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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