Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PITX2Homeobox protein. (267 aa)    
Predicted Functional Partners:
ENSACIP00000025985
Catenin (cadherin-associated protein), beta 1.
    
 
 0.773
ENSACIP00000024614
Lymphoid enhancer-binding factor 1.
    
 
 0.615
ENSACIP00000017390
Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.
      
 0.603
ENSACIP00000004699
DAN domain family, member 5.
      
 0.599
ENSACIP00000015998
Lefty1.
   
  
 0.587
ENSACIP00000024632
T-box transcription factor 5a.
    
 
 0.579
ENSACIP00000014426
Pumilio RNA-binding family member 2.
    
   0.549
ENSACIP00000027154
Pumilio RNA-binding family member 1.
    
   0.549
ENSACIP00000023764
Leucine-rich repeats and transmembrane domains 2a.
      
 0.535
ENSACIP00000007861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
      
 0.518
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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