Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000003334Ankyrin repeat and sterile alpha motif domain containing 1B. (1296 aa)    
Predicted Functional Partners:
ENSACIP00000000357
Si:ch211-168d1.3.
    
  0.864
ENSACIP00000017898
Dolichyl-diphosphooligosaccharide--protein glycosyltransferase subunit 1; Subunit of the oligosaccharyl transferase (OST) complex that catalyzes the initial transfer of a defined glycan (Glc(3)Man(9)GlcNAc(2) in eukaryotes) from the lipid carrier dolichol- pyrophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation. N-glycosylation occurs cotranslationally and the complex associates with the Sec61 complex at the channel-forming translocon complex that mediates protein translocation across the en [...]
    
 
 0.799
ENSACIP00000025740
Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.
   
 0.680
CASK
Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.
   
 0.680
EGFLAM
EGF like, fibronectin type III and laminin G domains.
    
 
 0.674
ENSACIP00000025055
F-actin-capping protein subunit beta; F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments.
    
 
 0.671
ENSACIP00000027110
Sodium/potassium transporting ATPase interacting 1.
   
  
 0.666
ENSACIP00000030057
G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family.
      
 0.649
ENSACIP00000001771
Synaptic Ras GTPase activating protein 1b.
   
 
 0.632
ENSACIP00000003294
DAB2 interacting protein b.
   
 
 0.632
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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