Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ENSACIP00000003337LIM domain kinase 1a. (658 aa)    
Predicted Functional Partners:
ENSACIP00000013147
Cofilin 1; Belongs to the actin-binding proteins ADF family.
   
 0.987
ENSACIP00000028180
Cofilin 2 (muscle); Belongs to the actin-binding proteins ADF family.
   
 0.987
ENSACIP00000029594
ADF-H domain-containing protein; Belongs to the actin-binding proteins ADF family.
   
 0.964
ENSACIP00000013538
Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.937
ENSACIP00000025273
Rho-associated, coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.
    
 0.937
ENSACIP00000013100
Rho-associated, coiled-coil containing protein kinase 2b.
    
 0.934
ENSACIP00000013111
Phorbol-ester/DAG-type domain-containing protein.
    
 0.934
PAK3
Non-specific serine/threonine protein kinase.
    
 0.905
ENSACIP00000022121
Non-specific serine/threonine protein kinase.
    
 0.905
PAK2
P21 (RAC1) activated kinase 2; Belongs to the protein kinase superfamily.
    
 0.901
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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