Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000003382General transcription factor IIH, polypeptide 3. (289 aa)    
Predicted Functional Partners:
ENSACIP00000000162
Excision repair cross-complementation group 3.
   
 0.999
ENSACIP00000008736
General transcription factor IIH, polypeptide 2.
   
 0.999
ENSACIP00000008767
General transcription factor IIH, polypeptide 1.
    
 0.999
ENSACIP00000010245
Excision repair cross-complementation group 2.
    
 0.999
ENSACIP00000010434
General transcription factor IIH, polypeptide 5.
    
 0.999
ENSACIP00000011673
General transcription factor IIH subunit 4; Component of the general transcription and DNA repair factor IIH (TFIIH) core complex which is involved in general and transcription-coupled nucleotide excision repair (NER) of damaged DNA. Belongs to the TFB2 family.
   
 0.999
ENSACIP00000031342
CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex.
   
 0.992
ENSACIP00000024171
Cyclin H; Belongs to the cyclin family.
   
 0.990
ENSACIP00000021625
Xeroderma pigmentosum, complementation group C.
    
 0.978
ENSACIP00000018361
General transcription factor IIE, polypeptide 1, alpha.
   
 0.977
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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