Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000003392Cyclin-dependent kinase 2; Belongs to the protein kinase superfamily. (264 aa)    
Predicted Functional Partners:
ENSACIP00000030445
Cyclin A1; Belongs to the cyclin family.
   
 0.990
ENSACIP00000024245
Cyclin A2; Belongs to the cyclin family.
   
 0.987
ENSACIP00000011479
Cyclin E1; Belongs to the cyclin family.
   
 0.982
ENSACIP00000026160
Cyclin B1; Belongs to the cyclin family.
   
 0.981
ENSACIP00000007861
Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family.
   
 0.979
ENSACIP00000004062
S-phase kinase-associated protein 2, E3 ubiquitin protein ligase.
   
 0.976
ENSACIP00000002164
Cyclin E2; Belongs to the cyclin family.
   
 0.973
ENSACIP00000020810
E2F transcription factor 1.
   
 0.971
ENSACIP00000025350
Cyclin-dependent kinase inhibitor 1A.
   
 0.969
ENSACIP00000015237
Fizzy/cell division cycle 20 related 1b.
   
 0.967
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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