Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ENSACIP00000003465Advillin. (769 aa)    
Predicted Functional Partners:
ENSACIP00000030849
Conserved oligomeric Golgi complex subunit 6; Required for normal Golgi function.
   
 
 0.792
ENSACIP00000001901
Conserved oligomeric Golgi complex subunit 8; Belongs to the COG8 family.
    
 
 0.787
ENSACIP00000011108
Component of oligomeric golgi complex 3.
    
 
 0.787
ENSACIP00000026907
Phosphoinositide kinase, FYVE finger containing.
     
  0.772
ENSACIP00000003060
Twinfilin actin-binding protein 1a.
    
 0.609
ENSACIP00000024070
Uncharacterized protein.
    
 0.609
ASNA1
ATPase ASNA1; ATPase required for the post-translational delivery of tail- anchored (TA) proteins to the endoplasmic reticulum. Recognizes and selectively binds the transmembrane domain of TA proteins in the cytosol. This complex then targets to the endoplasmic reticulum by membrane-bound receptors, where the tail-anchored protein is released for insertion. This process is regulated by ATP binding and hydrolysis. ATP binding drives the homodimer towards the closed dimer state, facilitating recognition of newly synthesized TA membrane proteins. ATP hydrolysis is required for insertion. [...]
   
   0.603
ENSACIP00000013098
WASP actin nucleation promoting factor a.
    
 
 0.602
ENSACIP00000022193
WASP like actin nucleation promoting factor b.
    
 
 0.602
ENSACIP00000028567
WASP like actin nucleation promoting factor a.
    
 
 0.602
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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