Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
Genomic Predictions
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gene co-occurrence
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ENSACIP00000003548Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (227 aa)    
Predicted Functional Partners:
ENSACIP00000031385
CID domain-containing protein.
    
 0.995
ENSACIP00000023712
Cleavage and polyadenylation specific factor 6.
   
 0.991
CPSF7
RRM domain-containing protein.
   
 0.988
ENSACIP00000001862
FIP1 like 1b (S. cerevisiae).
   
 0.987
ENSACIP00000011857
Cleavage and polyadenylation specific factor 4.
    
 0.979
ENSACIP00000016510
Cleavage stimulation factor, 3' pre-RNA, subunit 2.
   
 0.952
ENSACIP00000011979
Cleavage and polyadenylation specificity factor subunit 2.
   
 0.941
ENSACIP00000002397
Cleavage stimulation factor, 3' pre-RNA, subunit 1.
     
 0.936
YTHDC2
YTH domain containing 2.
   
 0.923
ENSACIP00000010288
Zinc finger CCCH-type containing 4.
    
 0.922
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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