Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
ITM2CIntegral membrane protein 2C. (249 aa)    
Predicted Functional Partners:
ENSACIP00000002025
Uncharacterized protein.
      
 0.613
ENSACIP00000031108
Solute carrier family 35 member A5.
      
 0.598
ENSACIP00000004473
Cyclin G associated kinase.
    
   0.562
ENSACIP00000005826
NADH:ubiquinone oxidoreductase core subunit S7; Belongs to the complex I 20 kDa subunit family.
    
 
 0.522
ENSACIP00000013984
PDZ domain containing 11.
   
  
 0.485
ENSACIP00000015728
Ring finger protein 7.
    
   0.461
ENSACIP00000016167
Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.
      
 0.450
ENSACIP00000024103
Amyloid beta (A4) precursor-like protein 1.
   
 0.448
APP
Amyloid beta precursor protein.
   
 0.448
ENSACIP00000029517
Amyloid beta (A4) precursor protein b.
   
 0.448
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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