Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000003604Uncharacterized protein. (129 aa)    
Predicted Functional Partners:
ENSACIP00000011481
Non-structural maintenance of chromosomes element 4; Component of the SMC5-SMC6 complex, that promotes sister chromatid alignment after DNA damage and facilitates double-stranded DNA breaks (DSBs) repair via homologous recombination between sister chromatids.
   
 0.833
ENSACIP00000003370
SMC_N domain-containing protein.
    
 0.830
ENSACIP00000021724
NSE1 homolog, SMC5-SMC6 complex component.
    
 0.830
ENSACIP00000026431
NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase.
    
 0.826
ENSACIP00000007851
Si:dkey-119f1.1.
    
 0.784
ENSACIP00000011752
Structural maintenance of chromosomes 6.
    
 0.784
ENSACIP00000009836
Nerve growth factor receptor a (TNFR superfamily, member 16).
    
 0.734
ENSACIP00000021046
Structural maintenance of chromosomes protein.
    
 0.625
ENSACIP00000013594
UDP-glucose 6-dehydrogenase; Involved in the biosynthesis of glycosaminoglycans; hyaluronan, chondroitin sulfate, and heparan sulfate. Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.
     
  0.610
ENSACIP00000027648
Putative lipoyltransferase 2, mitochondrial; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. Belongs to the LipB family.
     
  0.607
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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