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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Score
ENSACIP00000003665Hypoxanthine phosphoribosyltransferase; Belongs to the purine/pyrimidine phosphoribosyltransferase family. (223 aa)    
Predicted Functional Partners:
ENSACIP00000015489
Guanylate kinase 1b.
    
 0.923
ENSACIP00000016949
Purine nucleoside phosphorylase; The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta- (deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.
  
 0.915
ENSACIP00000024494
Guanylate kinase 1a.
    
 0.912
ENSACIP00000016057
Guanine monophosphate synthase.
  
 
 0.910
ADSSL1
Adenylosuccinate synthetase isozyme 1; Component of the purine nucleotide cycle (PNC), which interconverts IMP and AMP to regulate the nucleotide levels in various tissues, and which contributes to glycolysis and ammoniagenesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.904
ENSACIP00000018916
Adenylosuccinate synthetase; Plays an important role in the de novo pathway and in the salvage pathway of purine nucleotide biosynthesis. Catalyzes the first commited step in the biosynthesis of AMP from IMP.
  
 
 0.904
ENSACIP00000024840
MGS domain-containing protein.
  
 
 0.902
ENSACIP00000018012
Thiopurine S-methyltransferase, tandem duplicate 1.
   
 0.894
ENSACIP00000004406
Laccase (multicopper oxidoreductase) domain containing 1.
  
 
  0.889
ENSACIP00000010998
Amidohydro-rel domain-containing protein.
    
 0.887
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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