Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
ENSACIP00000003789Transmembrane protein 39A. (495 aa)    
Predicted Functional Partners:
ENSACIP00000002427
Receptor expression-enhancing protein.
      
 0.620
ENSACIP00000022263
SEC63 homolog, protein translocation regulator.
      
 0.604
ENSACIP00000004169
DnaJ (Hsp40) homolog, subfamily C, member 18.
      
 0.569
ENSACIP00000013958
Rhomboid domain containing 3.
      
 0.564
ENSACIP00000017769
Kinesin family member 21B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.
      
 0.493
ENSACIP00000022285
C-type lectin domain containing 16A.
      
 0.493
ENSACIP00000004848
Phospholipase D family, member 6.
      
 0.464
ENSACIP00000012226
PLD phosphodiesterase domain-containing protein.
      
 0.464
ENSACIP00000013481
HGH1 homolog (S. cerevisiae).
      
 0.453
ENSACIP00000025994
Derlin; Functional component of endoplasmic reticulum-associated degradation (ERAD) for misfolded lumenal proteins. May act by forming a channel that allows the retrotranslocation of misfolded proteins into the cytosol where they are ubiquitinated and degraded by the proteasome; Belongs to the derlin family.
      
 0.451
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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