Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000003909Spermidine synthase; Belongs to the spermidine/spermine synthase family. (293 aa)    
Predicted Functional Partners:
ENSACIP00000014442
Ornithine decarboxylase 1; Belongs to the Orn/Lys/Arg decarboxylase class-II family.
  
 0.986
ENSACIP00000008560
S-adenosylmethionine decarboxylase proenzyme.
  
 
 0.970
SMOX
Spermine oxidase.
     
 0.962
ENSACIP00000003314
Spermine synthase.
  
 
0.959
MTAP
S-methyl-5'-thioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.
  
 
 0.959
ENSACIP00000013654
Aminoadipate-semialdehyde synthase.
   
 0.955
ENSACIP00000011782
Uncharacterized protein.
     
 0.953
ENSACIP00000001054
Spermidine/spermine N1-acetyltransferase family member 2b.
    
 0.949
ENSACIP00000002880
Spermidine/spermine N1-acetyltransferase 1.
    
 0.940
SAT1
Spermidine/spermine N1-acetyltransferase 1b.
    
 0.940
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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