Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ENSACIP00000003945Suppressor of cancer cell invasion. (563 aa)    
Predicted Functional Partners:
ENSACIP00000027273
AT hook, DNA binding motif, containing 1.
    
 
 0.875
ENSACIP00000009073
Endonuclease.
      
 0.684
ENSACIP00000008662
Uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae).
      
 0.638
ENSACIP00000031480
Mitochondrial ribosomal protein L23.
      
 0.621
ENSACIP00000018711
OTU deubiquitinase 3.
      
 0.601
PRDM15
PR/SET domain 15.
      
 0.590
ENSACIP00000014832
G protein-coupled receptor 101; Belongs to the G-protein coupled receptor 1 family.
      
 0.585
ENSACIP00000004450
Voltage-dependent calcium channel gamma-7 subunit; Regulates the activity of L-type calcium channels that contain CACNA1C as pore-forming subunit (By similarity). Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Shows specificity only for GRIA1 and GRIA2. Belongs to the PMP-22/EMP/MP20 family. CACNG subfamily.
    
   0.580
ENSACIP00000008080
Calcium channel, voltage-dependent, gamma subunit 5a.
    
   0.580
ENSACIP00000010232
PDZ binding kinase.
      
 0.573
Your Current Organism:
Amphilophus citrinellus
NCBI taxonomy Id: 61819
Other names: A. citrinellus, Archocentrus citrinellum, Cichlasoma citrinellum, Herichthys citrinellus, Heros citrinellus, Midas cichlid, red devil, red devil cichlid
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